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PubMed PMID: 30937854
Anticancer Drugs
2007 Jan 11
182431-12-5
Linifanib shows inhibitory to Kit
Nutlin 3a Size:10mg solid PubMed PMID: 30937854Nutlin 3a, also known as SML 0580, is an inhibitor of MDM2 (human homolog of murine double minute 2), which disrupts its interaction with p53, leading to the stabilization and activation of p53. Nutlin 3a activates the p53 pathway and efficiently induces apoptosis in tumours with amplified MDM2 gene and overexpression of MDM2 protein. Product information CAS Number: 675576 98 4 Molecular Weight: 581. 49 Formula: C30H30Cl2N4O4 Synonym: Nutlin 3a Nutlin
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